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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 2. Colistin

The purpose of this study was to investigate the pharmacokinetic properties of colistin following intrapulmonary administration of colistin sulfate in rats. Colistin was infused or delivered in nebulized form at a dose of 0.35 mg/kg of body weight in rats, and plasma drug concentrations were measure...

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Detalhes bibliográficos
Main Authors: Gontijo, Aline Vidal Lacerda, Grégoire, Nicolas, Lamarche, Isabelle, Gobin, Patrice, Couet, William, Marchand, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068596/
https://ncbi.nlm.nih.gov/pubmed/24798284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02819-14
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