Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6. Aminoglycosides

Amikacin and gentamicin pharmacokinetic behaviors after nebulization were determined by comparing plasma and pulmonary epithelial lining fluid (ELF) concentrations in rats after intratracheal and intravenous administrations. ELF areas under concentration-time curve were 874 and 162 times higher afte...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Marchand, Sandrine, Boisson, Matthieu, Mehta, Shachi, Adier, Christophe, Mimoz, Olivier, Grégoire, Nicolas, Couet, William
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153828/
https://ncbi.nlm.nih.gov/pubmed/30082284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01261-18
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