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Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5. Oseltamivir Carboxylate

The aim of this study was to determine the biopharmaceutical characteristics of oseltamivir carboxylate (OC) after pulmonary delivery. After OC bolus and intratracheal nebulization (NEB) in rats, blood was collected and bronchoalveolar lavages (BALs) were performed. Epithelial lining fluid (ELF) con...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Galindo Bedor, Danilo Cesar, Marchand, Sandrine, Lamarche, Isabelle, Laroche, Julian, Pereira de Santana, Davi, Couet, William
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958211/
https://ncbi.nlm.nih.gov/pubmed/27297482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00909-16
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