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Bumped Kinase Inhibitor 1294 Treats Established Toxoplasma gondii Infection

Toxoplasma gondii is a unicellular parasite that causes severe brain and eye disease. Current drugs for T. gondii are limited by toxicity. Bumped kinase inhibitors (BKIs) selectively inhibit calcium-dependent protein kinases of the apicomplexan pathogens T. gondii, cryptosporidia, and plasmodia. A l...

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書誌詳細
主要な著者: Doggett, J. Stone, Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Van Voorhis, Wesley C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068437/
https://ncbi.nlm.nih.gov/pubmed/24687502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01823-13
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