Extended-Spectrum Antiprotozoal Bumped Kinase Inhibitors: A Review

Many life-cycle processes in parasites are regulated by protein phosphorylation. Hence, disruption of essential protein kinase function has been explored for therapy of parasitic diseases. However, the difficulty of inhibiting parasite protein kinases to the exclusion of host orthologues poses a pra...

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Опубликовано в: :Exp Parasitol
Главные авторы: Van Voorhis, Wesley C., Doggett, J. Stone, Parsons, Marilyn, Hulverson, Matthew A., Choi, Ryan, Arnold, Samuel, Riggs, Michael W., Hemphill, Andrew, Howe, Daniel K., Mealey, Robert H., Lau, Audrey O. T., Merritt, Ethan A., Maly, Dustin J., Fan, Erkang, Ojo, Kayode K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498274/
https://ncbi.nlm.nih.gov/pubmed/28065755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2017.01.001
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