Extended-Spectrum Antiprotozoal Bumped Kinase Inhibitors: A Review

Many life-cycle processes in parasites are regulated by protein phosphorylation. Hence, disruption of essential protein kinase function has been explored for therapy of parasitic diseases. However, the difficulty of inhibiting parasite protein kinases to the exclusion of host orthologues poses a pra...

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Detalhes bibliográficos
Publicado no:Exp Parasitol
Main Authors: Van Voorhis, Wesley C., Doggett, J. Stone, Parsons, Marilyn, Hulverson, Matthew A., Choi, Ryan, Arnold, Samuel, Riggs, Michael W., Hemphill, Andrew, Howe, Daniel K., Mealey, Robert H., Lau, Audrey O. T., Merritt, Ethan A., Maly, Dustin J., Fan, Erkang, Ojo, Kayode K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498274/
https://ncbi.nlm.nih.gov/pubmed/28065755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2017.01.001
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