Bumped Kinase Inhibitor 1294 Treats Established Toxoplasma gondii Infection

Toxoplasma gondii is a unicellular parasite that causes severe brain and eye disease. Current drugs for T. gondii are limited by toxicity. Bumped kinase inhibitors (BKIs) selectively inhibit calcium-dependent protein kinases of the apicomplexan pathogens T. gondii, cryptosporidia, and plasmodia. A l...

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Bibliografiske detaljer
Main Authors: Doggett, J. Stone, Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Van Voorhis, Wesley C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068437/
https://ncbi.nlm.nih.gov/pubmed/24687502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01823-13
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