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Nonnucleoside Inhibitors of Norovirus RNA Polymerase: Scaffolds for Rational Drug Design
Norovirus (NoV) is the leading cause of acute gastroenteritis worldwide, causing over 200,000 deaths a year. NoV is nonenveloped, with a single-stranded RNA genome, and is primarily transmitted person to person. The viral RNA-dependent RNA polymerase (RdRp) is critical for the production of genomic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068436/ https://ncbi.nlm.nih.gov/pubmed/24637690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02799-13 |
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