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Cross-Genotypic Examination of Hepatitis C Virus Polymerase Inhibitors Reveals a Novel Mechanism of Action for Thumb Binders

Direct-acting antivirals (DAAs) targeting proteins encoded by the hepatitis C virus (HCV) genome have great potential for the treatment of HCV infections. However, the efficacy of DAAs designed to target genotype 1 (G1) HCV against non-G1 viruses has not been characterized fully. In this study, we i...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Eltahla, Auda A., Tay, Enoch, Douglas, Mark W., White, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249545/
https://ncbi.nlm.nih.gov/pubmed/25246395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03699-14
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