Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal

RUNX1/CBFβ (core binding factor [CBF]) is a heterodimeric transcription factor complex that is frequently involved in chromosomal translocations, point mutations, or deletions in acute leukemia. The mixed lineage leukemia (MLL) gene is also frequently involved in chromosomal translocations or partia...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhao, Xinghui, Chen, Aili, Yan, Xiaomei, Zhang, Yue, He, Fuhong, Hayashi, Yoshihiro, Dong, Yunzhu, Rao, Yalan, Li, Bo, Conway, Rajeana M., Maiques-Diaz, Alba, Elf, Shannon E., Huang, Nuomin, Zuber, Johannes, Xiao, Zhijian, Tse, William, Tenen, Daniel G., Wang, Qianfei, Chen, Wei, Mulloy, James C., Nimer, Stephen D., Huang, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067497/
https://ncbi.nlm.nih.gov/pubmed/24449215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-489575
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados