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Runx2 induces acute myeloid leukemia in cooperation with Cbfβ-SMMHC in mice
The core-binding factor (CBF) is a master regulator of developmental and differentiation programs, and CBF alterations are frequently associated with acute leukemia. The role of the CBF member RUNX2 in hematopoiesis is poorly understood. Genetic evidence suggests that deregulation of Runx2 may cause...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665897/ https://ncbi.nlm.nih.gov/pubmed/19179305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-162248 |
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