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Runx2 induces acute myeloid leukemia in cooperation with Cbfβ-SMMHC in mice

The core-binding factor (CBF) is a master regulator of developmental and differentiation programs, and CBF alterations are frequently associated with acute leukemia. The role of the CBF member RUNX2 in hematopoiesis is poorly understood. Genetic evidence suggests that deregulation of Runx2 may cause...

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Détails bibliographiques
Auteurs principaux: Kuo, Ya-Huei, Zaidi, Sayyed K., Gornostaeva, Svetlana, Komori, Toshihisa, Stein, Gary S., Castilla, Lucio H.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665897/
https://ncbi.nlm.nih.gov/pubmed/19179305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-162248
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