CBFβ-SMMHC creates aberrant megakaryocyte-erythroid progenitors prone to leukemia initiation in mice

Acute myeloid leukemia (AML) arises through multistep clonal evolution characterized by stepwise accumulation of successive alterations affecting the homeostasis of differentiation, proliferation, self-renewal, and survival programs. The persistence and dynamic clonal evolution of leukemia-initiatin...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Cai, Qi, Jeannet, Robin, Hua, Wei-Kai, Cook, Guerry J., Zhang, Bin, Qi, Jing, Liu, Hongjun, Li, Ling, Chen, Ching-Cheng, Marcucci, Guido, Kuo, Ya-Huei
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025900/
https://ncbi.nlm.nih.gov/pubmed/27443289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-693119
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