CBFβ-SMMHC creates aberrant megakaryocyte-erythroid progenitors prone to leukemia initiation in mice

Acute myeloid leukemia (AML) arises through multistep clonal evolution characterized by stepwise accumulation of successive alterations affecting the homeostasis of differentiation, proliferation, self-renewal, and survival programs. The persistence and dynamic clonal evolution of leukemia-initiatin...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Cai, Qi, Jeannet, Robin, Hua, Wei-Kai, Cook, Guerry J., Zhang, Bin, Qi, Jing, Liu, Hongjun, Li, Ling, Chen, Ching-Cheng, Marcucci, Guido, Kuo, Ya-Huei
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2016
Teme:
Myeloid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025900/
https://ncbi.nlm.nih.gov/pubmed/27443289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-693119
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