Multiple Sclerosis Autoantigen Myelin Basic Protein Escapes Control by Ubiquitination during Proteasomal Degradation

The vast majority of cellular proteins are degraded by the 26S proteasome after their ubiquitination. Here, we report that the major component of the myelin multilayered membrane sheath, myelin basic protein (MBP), is hydrolyzed by the 26S proteasome in a ubiquitin-independent manner both in vitro a...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Belogurov, Alexey, Kudriaeva, Anna, Kuzina, Ekaterina, Smirnov, Ivan, Bobik, Tatyana, Ponomarenko, Natalia, Kravtsova-Ivantsiv, Yelena, Ciechanover, Aaron, Gabibov, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Protein Synthesis and Degradation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067209/
https://ncbi.nlm.nih.gov/pubmed/24739384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544247
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller