Nalaganje...

The ubiquitin-proteasome system and activation of NF-κB: involvement of the ubiquitin ligase KPC1 in p105 processing and tumor suppression

The p50 subunit of nuclear factor-kappa B (NF-κB) is generated from processing of the p105 precursor. We identified KIP1 ubiquitination-promoting complex 1 (KPC1) as the ubiquitin (Ub) ligase mediating this process. Overexpression of KPC1 results in tumor suppression, probably due to the generation...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Main Authors: Kravtsova-Ivantsiv, Yelena, Ciechanover, Aaron
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905413/
https://ncbi.nlm.nih.gov/pubmed/27308511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1054552
Oznake: Označite
Brez oznak, prvi označite!