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Structural Motifs Involved in Ubiquitin-Mediated Processing of the NF-κB Precursor p105: Roles of the Glycine-Rich Region and a Downstream Ubiquitination Domain

The ubiquitin proteolytic system plays a major role in a variety of basic cellular processes. In the majority of these processes, the target proteins are completely degraded. In one exceptional case, generation of the p50 subunit of the transcriptional regulator NF-κB, the precursor protein p105 is...

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Detalhes bibliográficos
Main Authors: Orian, Amir, Schwartz, Alan L., Israël, Alain, Whiteside, Simon, Kahana, Chaim, Ciechanover, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84174/
https://ncbi.nlm.nih.gov/pubmed/10207090
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