The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification

The appropriate expression of the roughly 30,000 human genes requires multiple layers of control. The oncoprotein MYC, a transcriptional regulator, contributes to many of the identified control mechanisms, including the regulation of chromatin, RNA polymerases, and RNA processing. Moreover, MYC recr...

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Hlavní autoři: Ullius, Andrea, Lüscher-Firzlaff, Juliane, Costa, Ivan G., Walsemann, Gesa, Forst, Alexandra H., Gusmao, Eduardo G., Kapelle, Karsten, Kleine, Henning, Kremmer, Elisabeth, Vervoorts, Jörg, Lüscher, Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066752/
https://ncbi.nlm.nih.gov/pubmed/24782528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku312
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