The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification

The appropriate expression of the roughly 30,000 human genes requires multiple layers of control. The oncoprotein MYC, a transcriptional regulator, contributes to many of the identified control mechanisms, including the regulation of chromatin, RNA polymerases, and RNA processing. Moreover, MYC recr...

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Autors principals: Ullius, Andrea, Lüscher-Firzlaff, Juliane, Costa, Ivan G., Walsemann, Gesa, Forst, Alexandra H., Gusmao, Eduardo G., Kapelle, Karsten, Kleine, Henning, Kremmer, Elisabeth, Vervoorts, Jörg, Lüscher, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066752/
https://ncbi.nlm.nih.gov/pubmed/24782528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku312
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