Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP

The c-MYC oncoprotein regulates various aspects of cell behaviour by modulating gene expression. Here, we report the identification of the cAMP-response-element-binding protein (CBP) as a novel c-MYC binding partner. The two proteins interact both in vitro and in cells, and CBP binds to the carboxy-...

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Main Authors: Vervoorts, Jörg, Lüscher-Firzlaff, Juliane M., Rottmann, Sabine, Lilischkis, Richard, Walsemann, Gesa, Dohmann, Karen, Austen, Matthias, Lüscher, Bernhard
格式: Artigo
語言:Inglês
出版: 2003
主題:
Scientific Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1319176/
https://ncbi.nlm.nih.gov/pubmed/12776737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor821
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