Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

Myc oncoproteins promote cell cycle progression in part through the transcriptional up-regulation of the cyclin D2 gene. We now show that Myc is bound to the cyclin D2 promoter in vivo. Binding of Myc induces cyclin D2 expression and histone acetylation at a single nucleosome in a MycBoxII/TRRAP-dep...

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Detalhes bibliográficos
Main Authors: Bouchard, Caroline, Dittrich, Oliver, Kiermaier, Astrid, Dohmann, Karen, Menkel, Annette, Eilers, Martin, Lüscher, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312761/
https://ncbi.nlm.nih.gov/pubmed/11511535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.907901
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