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Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

Myc oncoproteins promote cell cycle progression in part through the transcriptional up-regulation of the cyclin D2 gene. We now show that Myc is bound to the cyclin D2 promoter in vivo. Binding of Myc induces cyclin D2 expression and histone acetylation at a single nucleosome in a MycBoxII/TRRAP-dep...

Täydet tiedot

Tallennettuna:
Julkaisussa:Genes Dev
Päätekijät: Bouchard, Caroline, Dittrich, Oliver, Kiermaier, Astrid, Dohmann, Karen, Menkel, Annette, Eilers, Martin, Lüscher, Bernhard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2001
Aiheet:
Research Communication
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312761/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11511535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.907901
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