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Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1

BACKGROUND: The Myc oncoprotein is a transcriptional regulator whose function is essential for normal development. Myc is capable of binding to 10% of the mammalian genome, and it is unclear how a developing embryo controls the DNA binding of its abundant Myc proteins in order to avoid Myc's po...

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Detalhes bibliográficos
Main Authors: Goodliffe, Julie M, Cole, Michael D, Wieschaus, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887537/
https://ncbi.nlm.nih.gov/pubmed/17519021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-40
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