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Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila
Aberrant accumulation of the Myc oncoprotein propels proliferation and induces carcinogenesis. In normal cells, however, an abundance of Myc protein represses transcription at the c-myc locus. Cancer cells often lose this autorepression. We examined the control of myc in Drosophila and show here tha...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315398/ https://ncbi.nlm.nih.gov/pubmed/16357214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1352305 |
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