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The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins

Transcriptional on and off states of HOX genes and other developmental control genes are maintained by antagonistic regulators encoded by trithorax group (trxG) and Polycomb group (PcG) genes. The trxG proteins Ash1 and hTRX and the PcG repressor E(z) are histone methyltransferases (HMTases) that me...

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Detalhes bibliográficos
Main Authors: Klymenko, Tetyana, Müller, Jürg
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299022/
https://ncbi.nlm.nih.gov/pubmed/15031712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400111
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