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The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins

Transcriptional on and off states of HOX genes and other developmental control genes are maintained by antagonistic regulators encoded by trithorax group (trxG) and Polycomb group (PcG) genes. The trxG proteins Ash1 and hTRX and the PcG repressor E(z) are histone methyltransferases (HMTases) that me...

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Détails bibliographiques
Auteurs principaux: Klymenko, Tetyana, Müller, Jürg
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299022/
https://ncbi.nlm.nih.gov/pubmed/15031712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400111
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