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Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l

Post-translational modifications of core histones participate in controlling the expression of genes. Methylation of lysine 4 of histone H3 (H3K4), together with acetylation of H3K27, is closely associated with open chromatin and gene transcription. H3K4 methylation is catalyzed by KMT2 lysine methy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lüscher-Firzlaff, Juliane, Chatain, Nicolas, Kuo, Chao-Chung, Braunschweig, Till, Bochyńska, Agnieszka, Ullius, Andrea, Denecke, Bernd, Costa, Ivan G., Koschmieder, Steffen, Lüscher, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547667/
https://ncbi.nlm.nih.gov/pubmed/31164666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44720-3
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