Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells

Nonhomologous end-joining (NHEJ) is a key pathway for efficient repair of DNA double-strand breaks (DSBs) and V(D)J recombination. NHEJ defects in humans cause immunodeficiency and increased cellular sensitivity to ionizing irradiation (IR) and are variably associated with growth retardation, microc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Felgentreff, Kerstin, Du, Likun, Weinacht, Katja G., Dobbs, Kerry, Bartish, Margarita, Giliani, Silvia, Schlaeger, Thorsten, DeVine, Alexander, Schambach, Axel, Woodbine, Lisa J., Davies, Graham, Baxi, Sachin N., van der Burg, Mirjam, Bleesing, Jack, Gennery, Andrew, Manis, John, Pan-Hammarström, Qiang, Notarangelo, Luigi D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066476/
https://ncbi.nlm.nih.gov/pubmed/24889605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323649111
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak