A carregar...
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends
XRCC4-null mice have a more severe phenotype than KU80-null mice. Here, we address whether this difference in phenotype is connected to nonhomologous end-joining (NHEJ). We used intrachromosomal substrates to monitor NHEJ of two distal double-strand breaks (DSBs) targeted by I-SceI, in living cells....
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409239/ https://ncbi.nlm.nih.gov/pubmed/18093953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708541104 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|