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Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4
DNA double-strand break (DSB) repair by nonhomologous end joining (NHEJ) requires the assembly of several proteins on DNA ends. Although biochemical studies have elucidated several aspects of the NHEJ reaction mechanism, much less is known about NHEJ in living cells, mainly because of the inability...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693708/ https://ncbi.nlm.nih.gov/pubmed/17124166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609061103 |
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