Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

DNA double-strand break (DSB) repair by nonhomologous end joining (NHEJ) requires the assembly of several proteins on DNA ends. Although biochemical studies have elucidated several aspects of the NHEJ reaction mechanism, much less is known about NHEJ in living cells, mainly because of the inability...

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Bibliografske podrobnosti
Main Authors: Mari, Pierre-Olivier, Florea, Bogdan I., Persengiev, Stephan P., Verkaik, Nicole S., Brüggenwirth, Hennie T., Modesti, Mauro, Giglia-Mari, Giuseppina, Bezstarosti, Karel, Demmers, Jeroen A. A., Luider, Theo M., Houtsmuller, Adriaan B., van Gent, Dik C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693708/
https://ncbi.nlm.nih.gov/pubmed/17124166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609061103
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