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C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties
The Ku70/80 heterodimer binds to DNA ends and attracts other proteins involved in the non-homologous end-joining (NHEJ) pathway of DNA double-strand break repair. We developed a novel assay to measure DNA binding and release kinetics using differences in Förster resonance energy transfer (FRET) of t...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7555691/ https://ncbi.nlm.nih.gov/pubmed/32937838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186725 |
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