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The I-TevI Nuclease and Linker Domains Contribute to the Specificity of Monomeric TALENs
Precise genome editing in complex genomes is enabled by engineered nucleases that can be programmed to cleave in a site-specific manner. Here, we fused the small, sequence-tolerant monomeric nuclease domain from the homing endonuclease I-TevI to transcription-like activator effectors (TALEs) to crea...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Genetics Society of America
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065259/ https://ncbi.nlm.nih.gov/pubmed/24739648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.011445 |
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