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Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI
I-TevI, the phage T4 td intron-encoded endonuclease, recognizes a lengthy DNA target and initiates intron mobility by introducing a double-strand break in the homing site. The enzyme uses both sequence and distance determinants to cleave the DNA 23–25 bp upstream of the intron insertion site. I-TevI...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124309/ https://ncbi.nlm.nih.gov/pubmed/12077294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082253699 |
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