Grb10 Promotes Lipolysis and Thermogenesis by Phosphorylation-dependent Feedback Inhibition of mTORC1

Identification of key regulators of lipid metabolism and thermogenic functions has important therapeutic implications for the current obesity and diabetes epidemic. Here we show that Grb10, a newly identified direct substrate of mechanistic/mammalian target of rapamycin (mTOR), is expressed highly i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Liu, Meilian, Bai, Juli, He, Sijia, Villarreal, Ricardo, Hu, Derong, Zhang, Chuntao, Yang, Xin, Liang, Huiyun, Slaga, Thomas, Yu, Yonghao, Zhou, Zhiguang, Blenis, John, Scherer, Philipp E., Dong, Lily Q., Liu, Feng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064112/
https://ncbi.nlm.nih.gov/pubmed/24746805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.03.018
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia