mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia

OBJECTIVE: Pharmacological agents targeting the mTOR complexes are used clinically as immunosuppressants and anticancer agents and can extend the lifespan of model organisms. An undesirable side effect of these drugs is hyperlipidemia. Although multiple roles have been described for mTOR complex 1 (...

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Detaylı Bibliyografya
Yayımlandı:Mol Metab
Asıl Yazarlar: Paolella, Lauren M., Mukherjee, Sarmistha, Tran, Cassie M., Bellaver, Bruna, Hugo, Mindy, Luongo, Timothy S., Shewale, Swapnil V., Lu, Wenyun, Chellappa, Karthikeyani, Baur, Joseph A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961719/
https://ncbi.nlm.nih.gov/pubmed/32029223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.12.003
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