Ribosomal protein–Mdm2–p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation

The tumor suppressor p53 has recently been shown to regulate energy metabolism through multiple mechanisms. However, the in vivo signaling pathways related to p53-mediated metabolic regulation remain largely uncharacterized. By using mice bearing a single amino acid substitution at cysteine residue...

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Dettagli Bibliografici
Autori principali: Liu, Yong, He, Yizhou, Jin, Aiwen, Tikunov, Andrey P., Zhou, Lishi, Tollini, Laura A., Leslie, Patrick, Kim, Tae-Hyung, Li, Lei O., Coleman, Rosalind A., Gu, Zhennan, Chen, Yong Q., Macdonald, Jeffrey M., Graves, Lee M., Zhang, Yanping
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060669/
https://ncbi.nlm.nih.gov/pubmed/24872453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315605111
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