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The anaphase-promoting complex/cyclosome is an E3 ubiquitin ligase for Mdm2
The Mdm2 proto-oncoprotein is the primary negative regulator for p53. While it is believed that Mdm2 degradation is regulated via its own E3 ubiquitin ligase activity, recent development of knock-in mouse models demonstrates that Mdm2 E3 ligase function is dispensable for self-degradation in vivo. H...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Landes Bioscience
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111701/ https://ncbi.nlm.nih.gov/pubmed/24804778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29106 |
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