The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition

NEDD4-like ubiquitin ligase 2 (NEDL2) is a HECT type ubiquitin ligase. NEDL2 enhances p73 transcriptional activity and degrades ATR kinase in lamin misexpressed cells. Compared with the important functions of other HECT type ubiquitin ligase, there is less study concerning the function and regulatio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lu, Li, Hu, Shaohua, Wei, Rongfei, Qiu, Xiao, Lu, Kefeng, Fu, Yesheng, Li, Hongchang, Xing, Guichun, Li, Dong, Peng, Ruiyun, He, Fuchu, Zhang, Lingqiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2013
विषय:
Protein Synthesis and Degradation
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861616/
https://ncbi.nlm.nih.gov/pubmed/24163370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472076
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