APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome

Error-free chromosome segregation depends on timely activation of the multi-subunit E3 ubiquitin ligase APC/C. Activation of the APC/C initiates chromosome segregation and mitotic exit by targeting critical cell-cycle regulators for destruction. The APC/C is the principle target of the mitotic check...

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Dettagli Bibliografici
Autori principali: Kops, Geert J. P. L., van der Voet, Monique, Manak, Michael S., van Osch, Maria H. J., Naini, Said M., Brear, Andrea, McLeod, Ian X., Hentschel, Dirk M., Yates, John R., van den Heuvel, Sander, Shah, Jagesh V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864710/
https://ncbi.nlm.nih.gov/pubmed/20392738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.061549
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