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p53 Regulation Goes Live—Mdm2 and MdmX Co-Star: Lessons Learned from Mouse Modeling
Classically, p53 is considered to be an overarching tumor suppressor gene, important in its role as a transcription factor for a number of genes critical for cell cycle arrest, apoptosis, and senescence. More recently, the scope of p53 function has been further broadened, with evidence emerging that...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publications
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494374/ https://ncbi.nlm.nih.gov/pubmed/23150755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912454732 |
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