Ribosomal protein–Mdm2–p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation

The tumor suppressor p53 has recently been shown to regulate energy metabolism through multiple mechanisms. However, the in vivo signaling pathways related to p53-mediated metabolic regulation remain largely uncharacterized. By using mice bearing a single amino acid substitution at cysteine residue...

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Detalhes bibliográficos
Main Authors: Liu, Yong, He, Yizhou, Jin, Aiwen, Tikunov, Andrey P., Zhou, Lishi, Tollini, Laura A., Leslie, Patrick, Kim, Tae-Hyung, Li, Lei O., Coleman, Rosalind A., Gu, Zhennan, Chen, Yong Q., Macdonald, Jeffrey M., Graves, Lee M., Zhang, Yanping
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060669/
https://ncbi.nlm.nih.gov/pubmed/24872453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315605111
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