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Nutrient availability dictates the regulation of metabolism by the ribosomal protein-MDM2-p53 pathway

Nutrient availability alters ribosomal biogenesis, causing ribosomal proteins to act as secondary messengers of nutrient response by binding to MDM2 and activating p53. Recent work suggests that the ribosomal protein (RP)-MDM2-p53 pathway responds to the deficiency or overabundance of nutrients thro...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Oncol
Prif Awduron: Franklin, Derek, Zhang, Yanping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150035/
https://ncbi.nlm.nih.gov/pubmed/30250882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1302904
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