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Nutrient availability dictates the regulation of metabolism by the ribosomal protein-MDM2-p53 pathway

Nutrient availability alters ribosomal biogenesis, causing ribosomal proteins to act as secondary messengers of nutrient response by binding to MDM2 and activating p53. Recent work suggests that the ribosomal protein (RP)-MDM2-p53 pathway responds to the deficiency or overabundance of nutrients thro...

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Publicat a:Mol Cell Oncol
Autors principals: Franklin, Derek, Zhang, Yanping
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150035/
https://ncbi.nlm.nih.gov/pubmed/30250882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1302904
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