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Nutrient availability dictates the regulation of metabolism by the ribosomal protein-MDM2-p53 pathway

Nutrient availability alters ribosomal biogenesis, causing ribosomal proteins to act as secondary messengers of nutrient response by binding to MDM2 and activating p53. Recent work suggests that the ribosomal protein (RP)-MDM2-p53 pathway responds to the deficiency or overabundance of nutrients thro...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Franklin, Derek, Zhang, Yanping
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150035/
https://ncbi.nlm.nih.gov/pubmed/30250882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1302904
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