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RP–MDM2–p53 Pathway: Linking Ribosomal Biogenesis and Tumor Surveillance

Ribosomal biogenesis is tightly associated with cellular activities, such as growth, proliferation, and cell cycle progression. Perturbations in ribosomal biogenesis can initiate so-called nucleolar stress. The process through which ribosomal proteins (RPs) transduce nucleolar stress signals via MDM...

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Publicat a:Trends Cancer
Autors principals: Liu, Yong, Deisenroth, Chad, Zhang, Yanping
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531060/
https://ncbi.nlm.nih.gov/pubmed/28741571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.03.002
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