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Runx1 exon 6–related alternative splicing isoforms differentially regulate hematopoiesis in mice

RUNX1 is an important transcription factor for hematopoiesis. There are multiple alternatively spliced isoforms of RUNX1. The best known isoforms are RUNX1a from use of exon 7A and RUNX1b and c from use of exon 7B. RUNX1a has unique functions due to its lack of C-terminal regions common to RUNX1b an...

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Библиографические подробности
Главные авторы: Komeno, Yukiko, Yan, Ming, Matsuura, Shinobu, Lam, Kentson, Lo, Miao-Chia, Huang, Yi-Jou, Tenen, Daniel G., Downing, James R., Zhang, Dong-Er
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055923/
https://ncbi.nlm.nih.gov/pubmed/24771859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-521252
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