Runx1 exon 6–related alternative splicing isoforms differentially regulate hematopoiesis in mice

RUNX1 is an important transcription factor for hematopoiesis. There are multiple alternatively spliced isoforms of RUNX1. The best known isoforms are RUNX1a from use of exon 7A and RUNX1b and c from use of exon 7B. RUNX1a has unique functions due to its lack of C-terminal regions common to RUNX1b an...

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Hlavní autoři: Komeno, Yukiko, Yan, Ming, Matsuura, Shinobu, Lam, Kentson, Lo, Miao-Chia, Huang, Yi-Jou, Tenen, Daniel G., Downing, James R., Zhang, Dong-Er
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055923/
https://ncbi.nlm.nih.gov/pubmed/24771859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-521252
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