Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice

RUNX1 is a master transcription factor in hematopoiesis and mediates the specification and homeostasis of hematopoietic stem and progenitor cells (HSPCs). Disruptions in RUNX1 are well known to lead to hematologic disease. In this study, we sought to identify and characterize RUNX1 target genes in H...

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Detalhes bibliográficos
Main Authors: Lam, Kentson, Muselman, Alexander, Du, Randal, Harada, Yuka, Scholl, Amanda G., Yan, Ming, Matsuura, Shinobu, Weng, Stephanie, Harada, Hironori, Zhang, Dong-Er
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183983/
https://ncbi.nlm.nih.gov/pubmed/25150295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554543
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