Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice

RUNX1 is a master transcription factor in hematopoiesis and mediates the specification and homeostasis of hematopoietic stem and progenitor cells (HSPCs). Disruptions in RUNX1 are well known to lead to hematologic disease. In this study, we sought to identify and characterize RUNX1 target genes in H...

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Autori principali: Lam, Kentson, Muselman, Alexander, Du, Randal, Harada, Yuka, Scholl, Amanda G., Yan, Ming, Matsuura, Shinobu, Weng, Stephanie, Harada, Hironori, Zhang, Dong-Er
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2014
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183983/
https://ncbi.nlm.nih.gov/pubmed/25150295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554543
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