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Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells

HOXB4, a member of the Homeobox transcription factor family, promotes expansion of hematopoietic stem cells and hematopoietic progenitor cells in vivo and ex vivo when overexpressed. However, the molecular mechanisms underlying this effect are not well understood. To identify direct target genes of...

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Hlavní autoři: Jiang, Jie, Yu, Hui, Shou, Yan, Neale, Geoffrey, Zhou, Sheng, Lu, Taihe, Sorrentino, Brian P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918328/
https://ncbi.nlm.nih.gov/pubmed/20393131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235341
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