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Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

Brain development requires a precise balance between expansion of the neural progenitor pool and the production of postmitotic neurons and glia. Disruption of this equilibrium results in a myriad of structural abnormalities and disorders of the nervous system. The molecular mechanism that restricts...

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Detalhes bibliográficos
Main Authors: Lavado, Alfonso, He, Yu, Paré, Joshua, Neale, Geoffrey, Olson, Eric N., Giovannini, Marco, Cao, Xinwei
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737715/
https://ncbi.nlm.nih.gov/pubmed/23863479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.096537
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