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Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators
YAP and TAZ are transcription coactivators and effectors of the Hippo pathway, which play a key role in organ size control. Through interaction with transcription factors such as TEADs, they activate gene transcription and thus promote cell proliferation, inhibit apoptosis, and regulate cell differe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849657/ https://ncbi.nlm.nih.gov/pubmed/23985334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-33 |
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