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Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators

YAP and TAZ are transcription coactivators and effectors of the Hippo pathway, which play a key role in organ size control. Through interaction with transcription factors such as TEADs, they activate gene transcription and thus promote cell proliferation, inhibit apoptosis, and regulate cell differe...

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Hlavní autoři: Guo, Xiaocan, Zhao, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849657/
https://ncbi.nlm.nih.gov/pubmed/23985334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-33
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