The Hippo Pathway Prevents YAP/TAZ–Driven Hypertranscription and Controls Neural Progenitor Number

The Hippo pathway controls the activity of YAP/TAZ transcriptional coactivators through a kinase cascade. Despite the critical role of this pathway in tissue growth and tumorigenesis, it remains unclear how YAP/TAZ–mediated transcription drives proliferation. By analyzing the effects of inactivating...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Lavado, Alfonso, Park, Jun Young, Paré, Joshua, Finkelstein, David, Pan, Haitao, Xu, Beisi, Fan, Yiping, Kumar, Ram Parikshan, Neale, Geoffrey, Kwak, Young Don, McKinnon, Peter J., Johnson, Randy L., Cao, Xinwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296252/
https://ncbi.nlm.nih.gov/pubmed/30523785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.09.021
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