Integrin signalling regulates YAP and TAZ to control skin homeostasis

The skin is a squamous epithelium that is continuously renewed by a population of basal layer stem/progenitor cells and can heal wounds. Here, we show that the transcription regulators YAP and TAZ localise to the nucleus in the basal layer of skin and are elevated upon wound healing. Skin-specific d...

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Bibliografische gegevens
Gepubliceerd in:Development
Hoofdauteurs: Elbediwy, Ahmed, Vincent-Mistiaen, Zoé I., Spencer-Dene, Bradley, Stone, Richard K., Boeing, Stefan, Wculek, Stefanie K., Cordero, Julia, Tan, Ee H., Ridgway, Rachel, Brunton, Val G., Sahai, Erik, Gerhardt, Holger, Behrens, Axel, Malanchi, Ilaria, Sansom, Owen J., Thompson, Barry J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2016
Onderwerpen:
Stem Cells and Regeneration
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874484/
https://ncbi.nlm.nih.gov/pubmed/26989177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.133728
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