Integrin signalling regulates YAP and TAZ to control skin homeostasis

The skin is a squamous epithelium that is continuously renewed by a population of basal layer stem/progenitor cells and can heal wounds. Here, we show that the transcription regulators YAP and TAZ localise to the nucleus in the basal layer of skin and are elevated upon wound healing. Skin-specific d...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Development
Päätekijät: Elbediwy, Ahmed, Vincent-Mistiaen, Zoé I., Spencer-Dene, Bradley, Stone, Richard K., Boeing, Stefan, Wculek, Stefanie K., Cordero, Julia, Tan, Ee H., Ridgway, Rachel, Brunton, Val G., Sahai, Erik, Gerhardt, Holger, Behrens, Axel, Malanchi, Ilaria, Sansom, Owen J., Thompson, Barry J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Ltd 2016
Aiheet:
Stem Cells and Regeneration
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874484/
https://ncbi.nlm.nih.gov/pubmed/26989177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.133728
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