Cooperation between RUNX1-ETO9a and Novel Transcriptional Partner KLF6 in Upregulation of Alox5 in Acute Myeloid Leukemia

Fusion protein RUNX1-ETO (AML1-ETO, RUNX1-RUNX1T1) is expressed as the result of the 8q22;21q22 translocation [t(8;21)], which is one of the most common chromosomal abnormalities found in acute myeloid leukemia. RUNX1-ETO is thought to promote leukemia development through the aberrant regulation of...

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Bibliografiske detaljer
Main Authors: DeKelver, Russell C., Lewin, Benjamin, Lam, Kentson, Komeno, Yukiko, Yan, Ming, Rundle, Chandler, Lo, Miao-Chia, Zhang, Dong-Er
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794898/
https://ncbi.nlm.nih.gov/pubmed/24130502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003765
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